21st Nov, 2019
To date, there have been 12 RCTs comparing metabolic surgery to intensive medical management. We have highlighted a couple of those studies including the STAMPEDE trial from the Cleveland Clinic in prior newsletters, but this month gives a broader perspective and the Position Statement of International Diabetes Organizations on the role of metabolic surgery.   Below is depicted the profound effect of metabolic surgery in…
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24th Oct, 2019
In the recent 2019 paper published in JAMA, authors from the Cleveland Clinic reported on the care of over 13,000 individuals with type 2 diabetes. And similar to prior randomized controlled trials, and other large matched cohort studies, this carefully designed matched cohort study of diabetes care found large reductions in stoke, heart attack, mortality, and renal failure among patient undergoing metabolic surgery compared to…
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26th Sep, 2019
A look at the published results of the LOOK-AHEAD Trial. The NIH-sponsored LookAhead trial was a randomized controlled trial involving 5,145 individuals comparing an Intensive Lifestyle Intervention (ILI) to a Diabetes Support and Education (DSE) in overweight and obese type 2 diabetes patients to track the development of cardiovascular disease over time. The triaI intervention, at a cost of $15 million was stopped for futility…
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29th Aug, 2019
It is now widely known that metabolic surgery provides a profound reduction in type 2 diabetes metrics among obese individuals, with durable published remissions in a high percentage of patients beyond 10 years. Metabolic surgery reverses the type 2 diabetes completely in the first year in most obese individuals, and surgery induces a profound survival advantage, as well as dramatic reductions in blindness, kidney failure…
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25th Jun, 2019
It turns out that if you are under a non-surgical, medical management program for obesity, you are more than 7 times as likely to develop type 2 diabetes in the coming 7 years than if you were to undergo metabolic surgery. Similar rates of new-onset hypertension and hyperlipidemia occur, as reported in a recent paper in the Journal of the American Medical Association by Norwegian…
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8th Jan, 2019
Major long-term studies demonstrate diabetes remission after metabolic surgery with the sleeve gastrectomy, a 45-minute laparoscopic procedure. But patients rightly wish to know if that remission translates to meaningful gains in health and quantifiable reductions in end-organ diabetic disease, including renal, ophthalmological, and peripheral neuropathy complications. In the O’Brien matched cohort study published in the Annals of Internal Medicine, investigators studied more than 4,000 diabetic…
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5th Dec, 2018
With obesity and Type 2 diabetes continuing to grow as major health problems and causes of early morbidity and mortality, improved studies have examined longer follow-up time periods for diabetes remission after metabolic surgery. Sleeve gastrectomy is a 45-minute laparoscopy procedure. Ten-year studies help paint a picture of the durability of the remission rates for diabetes among individuals who undergo sleeve gastrectomy. Similar to other…
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8th Nov, 2018
recommendations for the treatment of type 2 diabetes. According to both the National Institutes of Health and the American Diabetes Association, bariatric surgery is recommended for all individuals with a BMI of 35 or more who have type 2 diabetes -without exceptions. Based on research that shows remission of diabetes even among lower-BMI individuals after metabolic surgery, the ADA also recommends bariatric surgery for individuals…
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16th Jan, 2017
diabetes treatments has made a profound impact, echoing around the corridors of many major medical centers and universities. The study, in which individuals with diabetes were randomized to receive either intensive medical treatment, sleeve gastrectomy, or gastric bypass surgery, closely monitored all the patients, and results were reported at one year, and three years. But the release of the most recent five-year data (See graph)…
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