fbpx

New Population Study Confirms Cancer Risk Reduction with Metabolic Surgery

Posted on: 26th Jul, 2019

Obese individuals suffer an increased risk of cancer, and an increase in cancer mortality compared to non-obese Americans. Now a large population-based study confirms that cancer incidence drops dramatically after metabolic surgery.

Numerous cohort studies have shown metabolic surgery decreases cancer risk. A previous large-scale prospectively matched 10-year surgical intervention trial identified that patients undergoing bariatric surgery had a significantly reduced risk of developing cancer (HR 0.67; 95% CI 0.53–0.85; p = 0.0009). The Swedish Obese Subjects study reinforced those findings. But the recent Wiggins meta-analysis paper involving over 635,000 patients represents the most conclusive analysis using population-based cohort studies. Among individual cancer types, breast cancer reduction was significant and pronounced as depicted below.

Obesity-related cancer is often defined as cancer of the breast, prostate, colorectum, endometrium, ovary, kidney, esophagus (adenocarcinoma only), liver, pancreas, gallbladder, non-Hodgkin lymphoma, leukemia, and thyroid. There is cohort data supporting this list but cohort, mechanism, and now population studies demonstrate breast cancer reduction from metabolic surgery and aggregate all cancer.
 
The mechanisms responsible for the reduction in cancer incidence associated with bariatric surgery are believed to be multifactoral. This effect is believed to be related to reduced systemic inflammation and oxidative stress, as well as the influence of surgery upon insulin resistance, sex steroids, gut hormones, and adipokines.
 
Metabolic surgery today consists of a 45-minute procedure with 4 Band-aids that is safer than Caesarian section and most routine operations, and it is safer than pharmaceutical management of type 2 diabetes in several large cohort papers.
 
 
References:
Sjöström, L., Gummesson, A., Sjöström, C.D., Narbro, K., Peltonen, M., Wedel, H., Bengtsson, C., Bouchard, C., Carlsson, B., Dahlgren, S. and Jacobson, P., 2009. Effects of bariatric surgery on cancer incidence in obese patients in Sweden (Swedish Obese Subjects Study): a prospective, controlled intervention trial. The lancet oncology, 10(7), pp.653-662.
 
Wiggins, T., Antonowicz, S.S. and Markar, S.R., 2019. Cancer Risk Following Bariatric Surgery—Systematic Review and Meta-analysis of National Population-Based Cohort Studies. Obesity surgery, 29(3), pp.1031-1039.

Similar Recent Posts

  • No, Bladder Leakage Isn’t “Normal”

    • sasse-surgical-reno-incontinence-solutions

      If a relative, or worse, a doctor, has told you that loss of bladder control or bowel control is simply a normal part of life or a normal part of aging, it’s time to examine the facts. Loss of bladder and bowel control is not normal. And today, there is a much better understanding of the Read More…

  • Is Weight-Loss Surgery Safe?

    • sasse-surgical-is-weight-loss-surgery-safe

      Anyone considering weight-loss surgery is going to have a lengthy list of questions, which is entirely appropriate. Chief among them relates to safety. Here’s the short answer – yes, weight-loss surgery, or metabolic surgery, is extremely safe. In fact, weight-loss surgery is safer than an appendectomy, a hernia repair, hysterectomy, and nearly every routine surgical procedure Read More…

  • The Problem with Resolving Bladder Leakage “Naturally”

    • sasse-surgical-problem-with-resolving-incontinence-naturally

      Incontinence is an issue affecting millions of men and women in the U.S. alone, and there are a number of solutions out there that  address the embarrassing symptoms of bladder and bowel leakage, instead of the issues themselves. You’ll also see much in the way of “natural” ways to address incontinence. Unfortunately, at some point, Read More…

Contact Us with any Questions Regarding your Bariatric Health

It is important that you give us your accurate weight and height, so we can best assist you.

There are Two Ways to Get Started
Actual Patient
Address
Sasse Surgical Associates
75 Pringle Way
Suite 804

Reno, NV 89502
Minimally invasive weight loss surgery experts.info@sassesurgical.com(775) 829-7999
Phone
Office Hours
Monday
7:30 am - 5:00 pm
Tuesday
7:30 am - 5:00 pm
Wednesday
7:30 am - 5:00 pm
Thursday
7:30 am - 5:00 pm
Friday
7:30 am - 3:00 pm
Saturday
Closed
Sunday
Closed