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26th Sep, 2019
A look at the published results of the LOOK-AHEAD Trial. The NIH-sponsored LookAhead trial was a randomized controlled trial involving 5,145 individuals comparing an Intensive Lifestyle Intervention (ILI) to a Diabetes Support and Education (DSE) in overweight and obese type 2 diabetes patients to track the development of cardiovascular disease over time. The triaI intervention, at a cost of $15 million was stopped for futility…
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29th Aug, 2019
It is now widely known that metabolic surgery provides a profound reduction in type 2 diabetes metrics among obese individuals, with durable published remissions in a high percentage of patients beyond 10 years. Metabolic surgery reverses the type 2 diabetes completely in the first year in most obese individuals, and surgery induces a profound survival advantage, as well as dramatic reductions in blindness, kidney failure…
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26th Jul, 2019
Obese individuals suffer an increased risk of cancer, and an increase in cancer mortality compared to non-obese Americans. Now a large population-based study confirms that cancer incidence drops dramatically after metabolic surgery. Numerous cohort studies have shown metabolic surgery decreases cancer risk. A previous large-scale prospectively matched 10-year surgical intervention trial identified that patients undergoing bariatric surgery had a significantly reduced risk of developing cancer…
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25th Jun, 2019
It turns out that if you are under a non-surgical, medical management program for obesity, you are more than 7 times as likely to develop type 2 diabetes in the coming 7 years than if you were to undergo metabolic surgery. Similar rates of new-onset hypertension and hyperlipidemia occur, as reported in a recent paper in the Journal of the American Medical Association by Norwegian…
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1st May, 2019
Obesity causes pain. A disproportionate number of people with obesity take opioids, and a disproportionate number of obese individuals undergo failed spine surgery. For some, it is a cycle of pain, opioids, depression, surgery, worsened pain, and so on. Researchers asked if metabolic surgery resulted in a significant reduction in chronic pain. Not surprisingly, the answer is metabolic surgery resulted in a large, sustained reduction…
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20th Mar, 2019
A 2018 study involving more than 17,000 patients shows a dramatic reduction in development of nephropathy and kidney failure among individuals with obesity and type 2 diabetes. When compared to standard medical management of obesity, diabetes and renal health, metabolic surgery resulted in a 3 -fold reduction in development of nephropathy over an average of 6 years. Standard medical management of diabetes and obesity has…
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22nd Feb, 2019
Macrovascular disease, including coronary artery disease and cerebrovascular disease, is a leading cause of morbidity and mortality among people with type 2 diabetes. And, as the Kaiser Permanente Health Research Institute researchers state in the introduction to this study, medical management, including lifestyle change, may not actually be successful at reducing the risk. In the 2018 Fisher matched cohort study published in the Journal the…
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8th Jan, 2019
Major long-term studies demonstrate diabetes remission after metabolic surgery with the sleeve gastrectomy, a 45-minute laparoscopic procedure. But patients rightly wish to know if that remission translates to meaningful gains in health and quantifiable reductions in end-organ diabetic disease, including renal, ophthalmological, and peripheral neuropathy complications. In the O’Brien matched cohort study published in the Annals of Internal Medicine, investigators studied more than 4,000 diabetic…
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5th Dec, 2018
With obesity and Type 2 diabetes continuing to grow as major health problems and causes of early morbidity and mortality, improved studies have examined longer follow-up time periods for diabetes remission after metabolic surgery. Sleeve gastrectomy is a 45-minute laparoscopy procedure. Ten-year studies help paint a picture of the durability of the remission rates for diabetes among individuals who undergo sleeve gastrectomy. Similar to other…
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21st Nov, 2018
Intensive medical management of Type 2 diabetes at the Cleveland Clinic consists of intensive tight control medical management with oral and injectable medication including GLP-1 agonists, together with dietary counseling and modification, an exercise program and support groups. This strategy was compared to metabolic surgery in a randomized, prospective controlled trial called the Stampede Trial published in the New England Journal of Medicine. 150 patients with…
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